Tuberculosis is a life-threatening disease that leads to ∼1.5 million annual human deaths, caused by Mycobacterium tuberculosis (Mtb). A common practice to treat this disease is to use antibiotics, half of which target the ribosome. To design ribosome-targeting antibiotics that potently and selectively kill Mtb without affecting the host, researchers need information on the structure… Read More →
Cell-cycle control of lipogenic enzymes at the level or protein synthesis
A new paper, spearheaded by Michael Polymenis’ lab here in Bio/Bio, has recently appeared in The EMBO Journal. Underscoring the collaborative nature of research at Texas A&M, critical contributors to the study include Brian Kennedy’s lab at the Buck Institute for Research on Aging, Prof. Rodolfo Aramayo’s lab from the Texas A&M Department of Biology,… Read More →
Single cell analysis of cell fate decisions in phage infection of bacteria
A new paper from Lanying Zeng, a member of the Center for Phage Technology and the Texas A&M Biochemistry and Biophysics Department has just appeared in Nature Communications. First author on the paper titled “Cell fate decisions emerge as phages cooperate or compete inside their host” is Jimmy Trinh, a Bio/Bio grad student. Critical contributions… Read More →
Molecular interactions in activation of the innate immune response
In conjunction with collaborators at Cincinnati Children’s Hospital Medical Center, Jun Yuan Ji’s lab at Texas A&M University Health Science Center, and elswhere, Bio/Bio’s Pingwei Li and colleagues have just published exciting new work in the Proceedings of the National Academy of Science. The paper, published online June 2, is entitled “Structural basis for concerted recruitment and… Read More →
Old drug may teach new tricks in treating infectious diseases and cancer
Meclizine, an over-the-counter drug used for decades to treat nausea and motion sickness, has the potential for new uses to treat certain infectious diseases and some forms of cancer, according to Dr. Vishal M. Gohil, an assistant professor of biochemistry and biophysics at Texas A&M University. “Clearly this drug has many potential new applications,” Gohil said…. Read More →