A new paper, spearheaded by Michael Polymenis’ lab here in Bio/Bio, has recently appeared in The EMBO Journal. Underscoring the collaborative nature of research at Texas A&M, critical contributors to the study include Brian Kennedy’s lab at the Buck Institute for Research on Aging, Prof. Rodolfo Aramayo’s lab from the Texas A&M Department of Biology, the Genomics/Bioinformatics Center at Texas A&M, and Prof. Vytas Bankaitis’ lab at Bio/Bio and TAMUHSC. The new work seeks to understand how regulation of proteins at the level of protein synthesis (translation) is coupled to the cell cycle. Cells grow and divide, and during this process they need to prepare for the increased demand for cellular building blocks that growth entails. Gene regulation can occur at many levels, but in this new work, first author Heidi Blank and coworkers reveal that enzymes for the synthesis of lipids, critical components of cellular membranes, are controlled at the level of their translation. This regulation was apparent because the new study very carefully, without using drugs or genetic perturbations, examined efficiency of protein synthesis across the cell cycle in a model organism, Baker’s yeast, by an elegant method to isolate newly born cells and follow them as they grow. This work was also highlighted in Agrilife Today.