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Ping He

He, Ping
Ping He
Borlaug/Room 179
Undergraduate Education
B.S. China Agricultural University (1993)
Graduate Education
M.S. Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (1998)
Ph.D. Kansas State University (2003)
Postdoc. Massachusetts General Hospital and Harvard Medical School (2003-2008)
Joined Texas A&M in 2009
NSF CAREER Award 2013

Signal Transduction in Plant Innate Immunity

Plants and animals, under constant attack by microbes, have evolved sophisticated immune systems to defend against infections. In turn, successful pathogens have developed elegant virulence strategies to suppress host immunity. Long-standing association between hosts and microbes has resulted in both acquiring specific adaptations which maximize their own survival and productivity.

Our laboratory is interested in elucidating novel plant immune signaling pathways as well as studying the myriad actions of pathogen virulence factors that intercept host immune responses. In order to provide a complete view of host-microbe interactions, we are using cellular, functional genomic, genetic, biochemical and bioinformatic approaches. In addition, plant immunity is inextricably linked with plant development and environmental stresses. We are also interested in understanding the signaling crosstalk that orchestrates plant responses to different extrinsic and intrinsic signals. Ultimately, knowledge gained from studying model plants, such as Arabidopsis, will be applied to improve crop plants for resistance against different biotic and abiotic stresses.

Recent Publications

  1. Zhou, J, Liu, D, Wang, P, Ma, X, Lin, W, Chen, S et al.. Regulation ofbrassinosteroid receptor BRI1 endocytosis and degradation by plant U-box PUB12/PUB13-mediated ubiquitination. Proc. Natl. Acad. Sci. U.S.A. 2018;115 (8):E1906-E1915.
    doi: 10.1073/pnas.1712251115. PubMed PMID:29432171. .

  2. Mang, H, Feng, B, Hu, Z, Boisson-Dernier, A, Franck, CM, Meng, X et al.. Differential Regulation of Two-Tiered Plant Immunity and Sexual Reproduction by ANXUR Receptor-Like Kinases. Plant Cell. 2017;29 (12):3140-3156.
    doi: 10.1105/tpc.17.00464. PubMed PMID:29150546. PubMed Central PMC5757273.

  3. Li, F, Li, M, Wang, P, Cox, KL Jr, Duan, L, Dever, JK et al.. Regulation of cotton (Gossypium hirsutum) drought responses by mitogen-activated protein (MAP) kinase cascade-mediated phosphorylation of GhWRKY59. New Phytol. 2017;215 (4):1462-1475.
    doi: 10.1111/nph.14680. PubMed PMID:28700082. .

  4. Cox, KL, Meng, F, Wilkins, KE, Li, F, Wang, P, Booher, NJ et al.. TAL effector driven induction of a SWEET gene confers susceptibility to bacterial blight of cotton. Nat Commun. 2017;8 :15588.
    doi: 10.1038/ncomms15588. PubMed PMID:28537271. PubMed Central PMC5458083.

  5. Yu, X, Feng, B, He, P, Shan, L. From Chaos to Harmony: Responses and Signaling upon Microbial Pattern Recognition. Annu Rev Phytopathol. 2017;55 :109-137.
    doi: 10.1146/annurev-phyto-080516-035649. PubMed PMID:28525309. .

  6. Hu, TX, Guo, X, Wang, G, Gao, L, He, P, Xia, Y et al.. MiR133b is involved in endogenous hydrogen sulfide suppression of sFlt-1 production in human placenta. Placenta. 2017;52 :33-40.
    doi: 10.1016/j.placenta.2017.02.012. PubMed PMID:28454695. .

  7. Michelmore, R, Coaker, G, Bart, R, Beattie, G, Bent, A, Bruce, T et al.. Foundational and Translational Research Opportunities to Improve Plant Health. Mol. Plant Microbe Interact. 2017;30 (7):515-516.
    doi: 10.1094/MPMI-01-17-0010-CR. PubMed PMID:28398839. PubMed Central PMC5810936.

  8. Feng, B, Liu, C, Shan, L, He, P. Protein ADP-Ribosylation Takes Control in Plant-Bacterium Interactions. PLoS Pathog. 2016;12 (12):e1005941.
    doi: 10.1371/journal.ppat.1005941. PubMed PMID:27907213. PubMed Central PMC5131896.

  9. Yadeta, KA, Elmore, JM, Creer, AY, Feng, B, Franco, JY, Rufian, JS et al.. A Cysteine-Rich Protein Kinase Associates with a Membrane Immune Complex and the Cysteine Residues Are Required for Cell Death. Plant Physiol. 2017;173 (1):771-787.
    doi: 10.1104/pp.16.01404. PubMed PMID:27852951. PubMed Central PMC5210739.

  10. Feng, B, Ma, S, Chen, S, Zhu, N, Zhang, S, Yu, B et al.. PARylation of the forkhead-associated domain protein DAWDLE regulates plant immunity. EMBO Rep. 2016;17 (12):1799-1813.
    doi: 10.15252/embr.201642486. PubMed PMID:27797852. PubMed Central PMC5283580.

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