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Ping He

He, Ping
Ping He
Borlaug/Room 179
Undergraduate Education
B.S. China Agricultural University (1993)
Graduate Education
M.S. Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (1998)
Ph.D. Kansas State University (2003)
Postdoc. Massachusetts General Hospital and Harvard Medical School (2003-2008)
Joined Texas A&M in 2009
NSF CAREER Award 2013

Signal Transduction in Plant Innate Immunity

Plants and animals, under constant attack by microbes, have evolved sophisticated immune systems to defend against infections. In turn, successful pathogens have developed elegant virulence strategies to suppress host immunity. Long-standing association between hosts and microbes has resulted in both acquiring specific adaptations which maximize their own survival and productivity.

Our laboratory is interested in elucidating novel plant immune signaling pathways as well as studying the myriad actions of pathogen virulence factors that intercept host immune responses. In order to provide a complete view of host-microbe interactions, we are using cellular, functional genomic, genetic, biochemical and bioinformatic approaches. In addition, plant immunity is inextricably linked with plant development and environmental stresses. We are also interested in understanding the signaling crosstalk that orchestrates plant responses to different extrinsic and intrinsic signals. Ultimately, knowledge gained from studying model plants, such as Arabidopsis, will be applied to improve crop plants for resistance against different biotic and abiotic stresses.

Recent Publications

  1. Hou, S, Jamieson, P, He, P. The cloak, dagger, and shield: proteases in plant-pathogen interactions. Biochem. J. 2018;475 (15):2491-2509.
    doi: 10.1042/BCJ20170781. PubMed PMID:30115747. .

  2. Xiong, C, Luo, D, Lin, A, Zhang, C, Shan, L, He, P et al.. A tomato B-box protein SlBBX20 modulates carotenoid biosynthesis by directly activating PHYTOENE SYNTHASE 1, and is targeted for 26S proteasome-mediated degradation. New Phytol. 2019;221 (1):279-294.
    doi: 10.1111/nph.15373. PubMed PMID:30101463. .

  3. Jamieson, PA, Shan, L, He, P. Plant cell surface molecular cypher: Receptor-like proteins and their roles in immunity and development. Plant Sci. 2018;274 :242-251.
    doi: 10.1016/j.plantsci.2018.05.030. PubMed PMID:30080610. .

  4. Lal, NK, Nagalakshmi, U, Hurlburt, NK, Flores, R, Bak, A, Sone, P et al.. The Receptor-like Cytoplasmic Kinase BIK1 Localizes to the Nucleus and Regulates Defense Hormone Expression during Plant Innate Immunity. Cell Host Microbe. 2018;23 (4):485-497.e5.
    doi: 10.1016/j.chom.2018.03.010. PubMed PMID:29649442. PubMed Central PMC6266874.

  5. Shan, L, He, P. Pipped at the Post: Pipecolic Acid Derivative Identified as SAR Regulator. Cell. 2018;173 (2):286-287.
    doi: 10.1016/j.cell.2018.03.045. PubMed PMID:29625046. .

  6. Zhou, J, Liu, D, Wang, P, Ma, X, Lin, W, Chen, S et al.. Regulation of Arabidopsis brassinosteroid receptor BRI1 endocytosis and degradation by plant U-box PUB12/PUB13-mediated ubiquitination. Proc. Natl. Acad. Sci. U.S.A. 2018;115 (8):E1906-E1915.
    doi: 10.1073/pnas.1712251115. PubMed PMID:29432171. PubMed Central PMC5828578.

  7. Mang, H, Feng, B, Hu, Z, Boisson-Dernier, A, Franck, CM, Meng, X et al.. Differential Regulation of Two-Tiered Plant Immunity and Sexual Reproduction by ANXUR Receptor-Like Kinases. Plant Cell. 2017;29 (12):3140-3156.
    doi: 10.1105/tpc.17.00464. PubMed PMID:29150546. PubMed Central PMC5757273.

  8. Li, F, Li, M, Wang, P, Cox, KL Jr, Duan, L, Dever, JK et al.. Regulation of cotton (Gossypium hirsutum) drought responses by mitogen-activated protein (MAP) kinase cascade-mediated phosphorylation of GhWRKY59. New Phytol. 2017;215 (4):1462-1475.
    doi: 10.1111/nph.14680. PubMed PMID:28700082. .

  9. Cox, KL, Meng, F, Wilkins, KE, Li, F, Wang, P, Booher, NJ et al.. TAL effector driven induction of a SWEET gene confers susceptibility to bacterial blight of cotton. Nat Commun. 2017;8 :15588.
    doi: 10.1038/ncomms15588. PubMed PMID:28537271. PubMed Central PMC5458083.

  10. Yu, X, Feng, B, He, P, Shan, L. From Chaos to Harmony: Responses and Signaling upon Microbial Pattern Recognition. Annu Rev Phytopathol. 2017;55 :109-137.
    doi: 10.1146/annurev-phyto-080516-035649. PubMed PMID:28525309. PubMed Central PMC6240913.

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