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February 2019

Biochemistry Seminar – Lance Wells : “Congenital Diseases of Unusual O-Glycosylation”

February 20 @ 4:00 pm - 5:00 pm
108 Biochemistry Building (Bldg.#1507), 300 Olsen Blvd
College Station, TX 77845 United States
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Lance Wells Department of Biochemistry and Molecular Biology University of Georgia, Athens   Title: "Congenital Diseases of Unusual O-Glycosylation" Abstract: Specific forms of muscular dystrophy and intellectual disability are caused by defects in glycosyltransferases. In this seminar, I will focus on recent discoveries delineating the various enzymes, structures and functions associated with O-mannose modified alpha-dystroglycan that when defective leads to various forms of congenital muscular dystrophy. Further, I'll discuss our recent work demonstrating that mutations in the gene encoding the…

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Biochemistry Seminar – Laurie K. Read : “Trypanosome RNA editing: the complexity of getting U in and taking U out”

February 27 @ 4:00 pm - 5:00 pm
108 Biochemistry Building (Bldg.#1507), 300 Olsen Blvd
College Station, TX 77845 United States
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Laurie K. Read Department of Microbiology & Immunology and Biochemistry University at Buffalo   Title: "Trypanosome RNA editing: the complexity of getting U in and taking U out" Abstract: Expression of most mitochondrial genes in trypanosomatid parasites requires extensive remodeling of mRNAs by Uridine-insertion/deletion (U-indel) editing to create translatable open reading frames. Editing is essential for parasite viability and virulence as edited mRNAs encode proteins involved in mitochondrial bioenergetics. The U-indel editing process entails several hundreds of small, non-coding mRNAs…

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March 2019

Biochemistry Seminar – Jason Brickner : ” Transcription factors and nuclear pores regulate the spatial organization of the yeast genome to facilitate epigenetic transcriptional regulation.”

March 6 @ 4:00 pm - 5:00 pm
108 Biochemistry Building (Bldg.#1507), 300 Olsen Blvd
College Station, TX 77845 United States
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Jason Brickner Department of Molecular Biosciences Northwestern University   Title: " Transcription factors and nuclear pores regulate the spatial organization of the yeast genome to facilitate epigenetic transcriptional regulation." Abstract:In eukaryotic organisms, many genes physically interact with nuclear pore proteins. In the model system budding yeast, up to 10% of genes physically interact with nuclear pore complexes (NPCs), localize at the nuclear periphery and often show NPC-dependent inter-chromosomal clustering with co-regulated genes. The interaction with the NPC can both promote…

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Biochemistry Seminar – Yungki Park : “Myrf (myelin regulatory factor): A story of a bioinformatician-turned neurobiologist”

March 20 @ 4:00 pm - 5:00 pm
108 Biochemistry Building (Bldg.#1507), 300 Olsen Blvd
College Station, TX 77845 United States
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Yungki Park Department of Biochemistry SUNY Buffalo   Title: "Myrf (myelin regulatory factor): A story of a bioinformatician-turned neurobiologist" Abstract: Myelination of the central nervous system (CNS) is critical to vertebrate nervous systems for efficient neural signaling. CNS myelination occurs as oligodendrocytes (OLs) terminally differentiate, a process regulated in part by the myelin regulatory factor, MYRF. In part I, I will discuss our discovery that Myrf is a membrane-bound transcription factor that undergoes auto-cleavage to release its N-terminal fragment from…

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Biochemistry Seminar – : “TBA”

March 27 @ 4:00 pm - 5:00 pm
108 Biochemistry Building (Bldg.#1507), 300 Olsen Blvd
College Station, TX 77845 United States
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Title: "TBA" Abstract: Host:BGA Location: 108 Biochemistry Building (Bldg#1507)

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Biophysical Society Spring Symposium

March 29

The Biophysical Research Symposium is a great opportunity for graduate students of all departments to show chase their research. This is a unique event for Texas A&M which will encourage research from all across campus to be put on display instead of focusing on one specific college or department. This symposium will feature a poster session and two oral presentation sessions. The first oral session will feature junior graduate students, giving them the rare opportunity to give a research talk…

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April 2019

Biochemistry Seminar – Peter Freddolino:” New surprises from the E. coli K12 genome”

April 3 @ 4:00 pm - 5:00 pm
108 Biochemistry Building (Bldg.#1507), 300 Olsen Blvd
College Station, TX 77845 United States
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Peter Freddolino Department of Biological Chemistry University of Michigan Medical School Title: " New surprises from the E. coli K12 genome" Abstract: Recent advances in high-throughput sequencing technology have yielded a huge increase in our knowledge of genomic sequences, but DNA sequence information remains meaningless without corresponding functional insight. It is only through a synthesis of computational approaches and high-throughput experiments that any meaningful headway can be made in the task of moving from genome sequence information to functional information…

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Biochemistry Seminar – Sean O’Leary : “Dynamics of mRNA recognition for translation initiation.”

April 10 @ 4:00 pm - 5:00 pm
108 Biochemistry Building (Bldg.#1507), 300 Olsen Blvd
College Station, TX 77845 United States
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Sean O'Leary Department of Biochemistry University of California, Riverside   Title : "Dynamics of mRNA recognition for translation initiation." Abstract: Recognition of the mRNA cap by protein factors plays a central role in the mechanism of eukaryotic translation initiation. Cap recognition is a complex, dynamic, multi-step, multi-component process that is extensively regulated to control gene expression. Importantly, different mRNAs are recognized with different efficiencies, and for individual mRNAs recognition efficiency can be modulated in response to cellular stimuli. This allows…

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Biochemistry Seminar – Alex Evilevitch: “Herpesvirus infectivity facilitated by internal DNA pressure and capsid stability”

April 17 @ 4:00 pm - 5:00 pm
108 Biochemistry Building (Bldg.#1507), 300 Olsen Blvd
College Station, TX 77845 United States
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Alex Evilevitch Department of Pathobiology and Physics University of Illinois   Title:"Herpesvirus infectivity facilitated by internal DNA pressure and capsid stability" Abstract: Herpesviruses are a leading cause of human viral disease, second only to influenza and cold viruses. Herpesviruses consist of a double-stranded (ds) DNA genome contained within a protein shell, termed the capsid, that is surrounded by an unstructured protein layer (the tegument) and a lipid-envelope. During viral replication, an ATP-dependent motor packages the genome into a preformed capsid…

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Biochemistry Seminar – Scot Leary: “TBA”

April 24 @ 4:00 pm - 5:00 pm
108 Biochemistry Building (Bldg.#1507), 300 Olsen Blvd
College Station, TX 77845 United States
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Scot Leary Department of Biochemistry, Microbiology and Immunology University of Saskatchewan Title: "TBA" Abstract: Host:Vishal Gohil Location: 108 Biochemistry Building (Bldg#1507)

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