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Biochemistry Seminar – Dr. Gregg Howe:”Molecular mechanism of jasmonate signaling: new insights into the dilemma of plants to grow or defend”
October 2 @ 4:00 pm - 5:00 pm
Dr. Gregg Howe
Department of Biochemistry & Molecular Biology
Michigan State University
Title: “Molecular mechanism of jasmonatae signaling: new insights into the dilemma of plants to grow or defend”
Abstract: The plant hormone jasmonate coordinates immune and growth responses to increase plant survival in unpredictable environments. The potency with which jasmonate both promotes defense and simultaneously inhibits growth implies a broader role for the hormone in controlling resource allocation to various physiological tasks. In this seminar, I will first describe the core functional and structural modules of the jasmonate signaling pathway, including COI1-JAZ coreceptors, JAZ-interacting transcription factors that execute physiological responses, and negative feedback loops to ensure timely termination of these responses. I will then discuss our recent progress in understanding how jasmonate-mediated transcriptional responses are specific, tunable, and evolvable. Finally, I will consider how this mechanistic foundation can accelerate the rational design of jasmonate signaling for improving crop resilience and harnessing the wellspring of specialized plant metabolites.
Host: Timothy Devarenne
108 Biochemistry Building (Bldg.#1507)