Dr. Chris Welch
Welch Innovation, LLC
Title: “High Throughput Analysis and High Throughput Experimentation in Pharmaceutical Development ”
Recent years have seen a fundamental shift in research strategies for the development and commercialization of new medicines, from a slower ‘one-at-a-time’ handcrafted approach to the widespread adoption of high throughput research methodologies. An overview of recent progress in this field is presented, with case histories illustrating how diverse areas of research such as synthetic route discovery and optimization, enzyme evolution and screening of catalysis crystallization and purification treatments have adopted and adapted high throughput experimentation approaches. Particular emphasis will be placed on the development of innovative high throughput analysis methodologies that allow scoring and assessment to keep pace with the speed of high throughput experimentation.
Bio: Christopher J. Welch is Chief Scientific Officer with Welch Innovation, LLC (www.welchinnovation.com) specializing in separation science, stereochemistry, high throughput experimentation, pharmaceutical analysis and process research. Dr. Welch has worked in a variety of fields within the chemical industry, ranging from agrochemicals (Velsicol-Sandoz) to diagnostics (Abbott) to small chemical businesses (Regis Technologies) to pharmaceuticals (Merck & Co., Inc.). While at Merck, Dr. Welch invented and applied new purification, analysis and high throughput experimentation technologies for pharmaceutical process research, also creating and administering Merck’s postdoctoral research fellows program and managing a multi-million dollar fund and research network that identified, evaluated and acquired new enabling technologies for pharmaceutical discovery and development. Dr. Welch currently serves on the Scientific Advisory Board for Snapdragon Chemistry, as a Science Advisor for Shimadzu Scientific Instruments Worldwide Innovation Centers, and as a Science Advisor for U.S. Food and Drug Administration Northeast Food & Feed Lab and Northeast Medical Products Lab. He has authored more than 275 scientific publications and patents, and serves on the boards of a number of journals and professional societies. He is a Fellow of the American Chemical Society (ACS), Fellow of the American Association for the Advancement of Science (AAAS) and the recipient of a number of awards, including the Chirality Medal and the 2017 EAS Award in Separation Science.
Location: 108 Biochemistry Building (Bldg#1507)