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Biochemistry Seminar : Wenshe Liu – :”Using an expanded genetic code to study epigenetic modifications”
January 30 @ 4:00 pm - 5:00 pm
Department of Chemistry
Texas A&M University
Title: Using an expanded genetic code to study epigenetic modifications
Abstract:Using molecular biology in combination with chemical transformation, multiple strategies were developed for the synthesis of histones with site-specific lysine modifications. Using nucleosomes assembled from these histones has allowed the characterization of sirtuins, a group of histone deacetylases.