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Biochemistry Seminar – Lance Wells : “Congenital Diseases of Unusual O-Glycosylation”

February 20 @ 4:00 pm - 5:00 pm

Lance Wells

Department of Biochemistry and Molecular Biology

University of Georgia, Athens


Title: “Congenital Diseases of Unusual O-Glycosylation”

Specific forms of muscular dystrophy and intellectual disability are caused by defects in glycosyltransferases. In this seminar, I will focus on recent discoveries delineating the various enzymes, structures and functions associated with O-mannose modified alpha-dystroglycan that when defective leads to various forms of congenital muscular dystrophy. Further, I’ll discuss our recent work demonstrating that mutations in the gene encoding the O-GlcNAc transferase, which modifies nuclear and cytoplasmic proteins, are causal for X-linked intellectual disability.

Host: Vlad Panin

Location: 108 Biochemistry Building (Bldg#1507)



February 20
4:00 pm - 5:00 pm


Vlad Panin


108 Biochemistry Building (Bldg.#1507)
300 Olsen Blvd
College Station, TX 77845 United States
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