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Biochemistry Seminar – Dr. Amanda Haes : “Nanoparticles and SERS – To Stability and Beyond!”
October 30 @ 4:00 pm - 5:00 pm
Dr. Amanda Haes
Department of Chemistry
University of Iowa
Title: “Nanoparticles and SERS – To Stability and Beyond!”
Abstract: Anisotropic nanostructures such as gold nanostars exhibit large surface energies relative to spheres or larger structures, thus flocculation and restructuring over time are likely. Restructuring, for instance, most likely occurs at regions of high surface free energy such as those at the nanostar tips because of their small radius of curvatures. As such, the tips on gold nanostars can dissolve more quickly than other portions of the structures in some conditions. With the growing inclusion and use of these nanoparticles in products and devices, developing characterization tools and experimental methods that can be used to predict nanoparticle stability fate are increasingly important. Two challenges and approaches to better predict structure-function behavior of noble metal nanoparticles will be discussed. A combination of experimental measurements that provide molecular-level insight coupled with semi-empirical modeling will be shown to improve the systematic use of gold nanostars by providing a method for predicting the stability and hence, the fate of nanomaterials in various environmental conditions. After these considerations, localized surface plasmon resonance (LSPR) spectroscopy and surface enhanced Raman scattering (SERS) will be exploited for the direct, qualitative and quantitative detection of small biologically relevant molecules. In the future, these results could be expanded for different nanomaterial shapes, compositions, and molecular targets.
Biochemistry Building (Bldg#1507)