Biochemistry & Biophysics

Recent publications

Some recent publications from BioBio labs are listed below. For a more extensive list, click here.

  1. Major DT, Heroux A, Orville AM, Valley MP, Fitzpatrick PF & Gao J (2009) Differential quantum tunneling contributions in nitroalkane oxidase catalyzed and the uncatalyzed proton transfer reaction. Proc Natl Acad Sci U S A
  2. Volbeda A, Darnault C, Tan X, Lindahl PA & Fontecilla-Camps JC (2009) Correction to Novel Domain Arrangement in the Crystal Structure of a Truncated Acetyl-CoA Synthase from Moorella thermoacetica. Biochemistry
  3. Henderson Pozzi M, Gawandi V & Fitzpatrick PF (2009) Mechanistic Studies of para-Substituted N,N'-Dibenzyl-1,4-diaminobutanes as Substrates for a Mammalian Polyamine Oxidase. Biochemistry
  4. Fenton AW & Reinhart GD (2009) Disentangling the Web of Allosteric Communication in a Homotetramer: Heterotropic Inhibition in Phosphofructokinase from Eschericia coli. Biochemistry
  5. Sun Q, Kuty GF, Arockiasamy A, Xu M, Young R & Sacchettini JC (2009) Regulation of a muralytic enzyme by dynamic membrane topology. Nat Struct Mol Biol 16: 1192-4
  6. Pang T, Savva CG, Fleming KG, Struck DK & Young R (2009) Structure of the lethal phage pinhole. Proc Natl Acad Sci U S A 106: 18966-71
  7. Surovtseva YV, Churikov D, Boltz KA, Song X, Lamb JC, Warrington R, Leehy K, Heacock M, Price CM & Shippen DE (2009) Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes. Mol Cell 36: 207-18
  8. Hernandez A, Madina BR, Ro K, Wohlschlegel JA, Willard B, Kinter MT & Cruz-Reyes J (2009) REH2 RNA helicase in kinetoplastid mitochondria: ribonucleoprotein complexes and essential motifs for unwinding and guide RNA binding. J Biol Chem
  9. Miao R, Kim H, Koppolu UM, Ellis EA, Scott RA & Lindahl PA (2009) Biophysical characterization of the iron in mitochondria from Atm1p-depleted Saccharomyces cerevisiae. Biochemistry 48: 9556-68
  10. Reddy MC, Palaninathan SK, Bruning JB, Thurman C, Smith D & Sacchettini JC (2009) Structural insights into the mechanism of the allosteric transitions of the mycobacterium tuberculosis cAMP receptor protein. J Biol Chem
  11. Nguyen TT, Fedorov AA, Williams L, Fedorov EV, Li Y, Xu C, Almo SC & Raushel FM (2009) The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry 48: 8879-90
  12. Volbeda A, Darnault C, Tan X, Lindahl PA & Fontecilla-Camps JC (2009) Novel domain arrangement in the crystal structure of a truncated acetyl-CoA synthase from Moorella thermoacetica. Biochemistry 48: 7916-26
  13. Payne K, Sun Q, Sacchettini J & Hatfull GF (2009) Mycobacteriophage Lysin B is a novel mycolylarabinogalactan esterase. Mol Microbiol 73: 367-81
  14. Cummings JA, Fedorov AA, Xu C, Brown S, Fedorov E, Babbitt PC, Almo SC & Raushel FM (2009) Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily. Biochemistry 48: 6469-81
  15. Gaweska H, Henderson Pozzi M, Schmidt DM, McCafferty DG & Fitzpatrick PF (2009) Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1. Biochemistry 48: 5440-5
  16. Zheng Y, Struck DK & Young R (2009) Purification and functional characterization of phiX174 lysis protein E. Biochemistry 48: 4999-5006
  17. Wang S, Sura GR, Dangott LJ & Fitzpatrick PF (2009) Identification by hydrogen/deuterium exchange of structural changes in tyrosine hydroxylase associated with regulation. Biochemistry 48: 4972-9
  18. Xiang DF, Xu C, Kumaran D, Brown AC, Sauder JM, Burley SK, Swaminathan S & Raushel FM (2009) Functional annotation of two new carboxypeptidases from the amidohydrolase superfamily of enzymes. Biochemistry 48: 4567-76
  19. Flanagan JJ, Tweten RK, Johnson AE & Heuck AP (2009) Cholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O binding. Biochemistry 48: 3977-87
  20. Xiang DF, Patskovsky Y, Xu C, Meyer AJ, Sauder JM, Burley SK, Almo SC & Raushel FM (2009) Functional identification of incorrectly annotated prolidases from the amidohydrolase superfamily of enzymes. Biochemistry 48: 3730-42
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