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Biochem - Week of 11/15/2009
Wed Nov 18 2009 4:00 PMBioBio 108
Speaker: Roger Innes, Department of Biology, Indiana University
Title :"Molecular Mechanisms Underlying Pathogen Recognition in Plants"
Host: Ping He
Sunday's hot paper
Major DT, Heroux A, Orville AM, Valley MP, Fitzpatrick PF & Gao J (2009) Differential quantum tunneling contributions in nitroalkane oxidase catalyzed and the uncatalyzed proton transfer reaction. Proc Natl Acad Sci U S AChanges daily; picked from the most recent notable papers from BioBio labs.
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The Shippen lab studies telomere function, maintenance and formation.Telomeres prevent chromosome ends from being identified as broken DNA and repaired. The telomerase enzyme in Arabidopsis has several components including a RNA molecule that contains a template region and a protein called telomerase reverse transcriptase (TERT) that uses the sequence on the RNA to add the complementary DNA sequence to the chromosome end. These two subunits and the various other components have to be assembled before telomerase is able to function. In this image, TERT molecules in Arabidopsis nuclei are visualized by immunofluorescence. The Tert molecules are located in the nucleolus, the same place that ribosomes are put together.